I keep seeing these two compared in longevity circles. Both activate AMPK, both improve insulin sensitivity. Metformin has the TAME trial coming but berberine has …
Following the Mayo Clinic dosing protocol: 20mg/kg for 2 consecutive days, repeated monthly. I've done 4 cycles now. Subjectively, I notice reduced joint stiffness for …
The Dog Aging Project just published their latest rapamycin results. The treated group showed significantly better cardiac function and owner-reported activity levels. What's interesting is …
https://www.nature.com/articles/example…Large meta-analyses keep showing that vitamin D supplementation reduces all-cause mortality by ~6%. The VITAL trial showed reduced cancer mortality. Yet most longevity experts barely …
My total T was 420 ng/dL at age 38. After 3 months of tongkat ali (400mg standardized extract), it went up to 510. I also …
Empagliflozin and dapagliflozin are showing remarkable results beyond diabetes. Cardioprotective, renoprotective, and some evidence of geroprotective effects. The mechanism (glucose wasting) essentially mimics caloric restriction …
I started taking 5g creatine monohydrate daily primarily for muscle preservation. Unexpected benefit: I feel noticeably sharper, especially in the afternoons when I usually hit …
I've been on 6mg weekly rapamycin for 6 months now under physician supervision. Sharing my full bloodwork panels (before/after), side effects I experienced, and subjective …
I took 500mg NMN daily for 4 months. Got intracellular NAD+ measured via Jinfiniti before and after. My levels went from 31 (below optimal) to …