17 points
Question Genetics & Genomics

Genetic testing for longevity — which service gives the most useful data?

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dr_mito 1 month, 2 weeks ago

I want to get genetic testing done with a focus on longevity-relevant variants (APOE, FOXO3, CETP, MTHFR, etc). 23andMe has been declining, Nebula offers whole genome sequencing, and SelfDecode focuses on health optimization. Has anyone compared these? I care more about actionable health insights than ancestry.

17 points 3 comments

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sleep_hacker · 1 month, 2 weeks ago · 11 pts

Knowing your APOE status is arguably the most actionable longevity genetic test. It directly affects your cardiovascular and Alzheimer's risk strategy.

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biohacker_sam · 1 month, 2 weeks ago · 8 pts

I did Nebula whole genome and used Promethease + SelfDecode for interpretation. The raw data is most valuable — services come and go but your genome doesn't change.

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epigenetic_age · 1 month, 2 weeks ago · 6 pts

Be prepared for results you might not want. I found out I'm APOE4/4 and it sent me into an anxiety spiral before I developed a proactive plan.