16 points

Has anyone tried the Prolon fasting-mimicking diet?

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My doctor recommended Prolon for its autophagy benefits. 5 days of restricted calories with specific macros. It's expensive ($250/cycle) and the food is pretty bland. For those who've done it — was it worth it vs just doing a 3-day water fast? I'm looking for both subjective experiences and any biomarker data you might have.

16 points 3 comments

Comments

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longev_nerd · 1 month, 3 weeks ago · 13 pts

Did two cycles. The convenience is the only real advantage over water fasting. The "food" is basically nut bars and soup. Save your money and just fast.

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senolytics_fan · 1 month, 3 weeks ago · 9 pts

The Valter Longo research behind it is legit, but you can replicate the macros yourself for a fraction of the cost. Lots of DIY FMD protocols online.

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nmn_skeptic · 1 month, 3 weeks ago · 6 pts

I actually prefer Prolon to water fasting because the small amount of food makes it much more sustainable. I do it quarterly and my IGF-1 drops significantly each time.