Goals in plastic surgery and aesthetic medicine include minimizing healing complications, optimize aesthetic outcomes and improve patient satisfaction. Platelet-derived growth factor BB (PDGF-BB) is among the most potent natural activators of healing. A pharmaceutical copy of natural PDGF-BB, (rhPDGF-BB or pure PDGF) is the active ingredient in four US Food and Drug Administration-approved therapies to stimulate healing of skin, mucosa, gingivae or bone. Here we describe the mechanism of action and clinical uses of off-the-shelf pure PDGF in plastic surgery and aesthetic medicine as a post-treatment adjunct to enhance patient satisfaction.
Clinical Applications of Pure Recombinant Human Platelet-Derived Growth Factor BB in Esthetic Medicine and Plastic Surgery.
TL;DR
Goals in plastic surgery and aesthetic medicine include minimizing healing complications, optimize aesthetic outcomes and improve patient satisfaction. Platelet-derived growth factor BB (PDGF-BB) is among the most potent natural activators of healing. A pharmaceutical copy of natural PDGF-BB, (rhPDGF-BB or pure PDGF) is the active ingredient in four US Food and Drug Administration-approved therapies to stimulate healing of skin, mucosa, gingivae or bone. Here we describe the mechanism of action
Credibility Assessment
Preliminary — 38/100
Study Design
Rigor of the research methodology
5/20
Sample Size
Whether the study was sufficiently powered
7/20
Peer Review
Review status and journal reputation
10/20
Replication
Has this finding been independently reproduced?
6/20
Transparency
Funding disclosure and data availability
10/20
Overall
Sum of all five dimensions
38/100
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