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Metformin TAME Trial Interim Results

TL;DR

Preliminary data shows metformin may delay onset of age-related diseases by 15-20%.

Credibility Assessment Verified — 83/100
Study Design
Rigor of the research methodology
19/20
Sample Size
Whether the study was sufficiently powered
20/20
Peer Review
Review status and journal reputation
18/20
Replication
Has this finding been independently reproduced?
8/20
Transparency
Funding disclosure and data availability
18/20
Overall
Sum of all five dimensions
83/100

What this means

Promising results but more studies needed.

The TAME trial is the first FDA-approved trial to target aging itself.

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