This RCT examined the effects of NMN supplementation in healthy adults aged 45-65.
NAD+ Precursors Show Promise in Human Trials
TL;DR
NMN supplementation increased blood NAD+ levels by 40% in middle-aged adults, with improvements in insulin sensitivity.
Credibility Assessment
Promising — 74/100
Study Design
Rigor of the research methodology
17/20
Sample Size
Whether the study was sufficiently powered
14/20
Peer Review
Review status and journal reputation
18/20
Replication
Has this finding been independently reproduced?
10/20
Transparency
Funding disclosure and data availability
15/20
Overall
Sum of all five dimensions
74/100
What this means
Promising results but more studies needed.
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