Senolytic combination therapy targeting senescent cells
Aging is a primary risk factor for disease progression in multiple sclerosis (MS). Because of this, treatments that can reduce the consequences of molecular aging, like senescence, have been proposed as a strategy to address …
Researchers treated female mice with fatty liver disease (MASLD) using senolytic drugs—compounds that eliminate senescent (aged) cells—and found pregnancy rates improved, particularly through reduced aging and inflammation in the ovaries. However, the treatment had limited …
Researchers tested whether dasatinib and quercetin—drugs that eliminate senescent (aging) cells—could prevent bone loss in the jaw. The treatment worked in naturally aged mice but failed in a gum disease model, suggesting senolytic benefits may …