A Dialectical Behavior Therapy Skills Training Intervention for Cigarette Smoking by Patients with Cancer: Focused Qualitative Inquiry Prior to Feasibility Trial

BackgroundDespite evidence that quitting smoking improves cancer treatment and outcomes, about one in eight patients with cancer smokes cigarettes. Barriers to quitting for patients with cancer include psychological distress such as anxiety and hopelessness and …

34 Early
Design 5
Sample 7
Peer Review 4
Replication 6
Transparency 12

Women's Alzheimer's Prevention: Lifestyle, Menopause, and Emerging Treatments

Lisa Mosconi discusses sex-specific Alzheimer's prevention strategies for midlife women, emphasizing behavioral interventions (exercise, sleep, nutrition, stress management) as the primary prevention tools while highlighting emerging pharmaceutical options like GLP-1 agonists and klotho.

Lisa Mosconi discusses sex-specific Alzheimer's prevention strategies for midlife women, emphasizing behavioral interventions (exercise, sleep, nutrition, stress management) as the primary prevention tools while highlighting emerging pharmaceutical options like GLP-1 agonists and klotho. The conversation …

50 Promising
Design 13
Sample 6
Peer Review 7
Replication 11
Transparency 13

Why Agency and Meaning Matter More Than Health Metrics in Old Age

This philosophical essay argues that later life should be understood as a valuable life stage defined by agency, meaning, and relationships—not reduced to health risks or frailty. The authors draw on Cicero's ancient treatise to …

29 Early
Design 4
Sample 2
Peer Review 11
Replication 2
Transparency 10

Can gaming communities reduce loneliness and depression in adults?

A 60-day online gaming community with professional facilitation reduced depression and anxiety symptoms by moderate amounts in adults who play video games, with about 21% of participants moving from moderate-to-severe depression into healthier ranges. While …

43 Early
Design 8
Sample 10
Peer Review 11
Replication 5
Transparency 9

Childhood Trauma's Long Shadow: Brain Changes Persist into Aging

Researchers found that people with multiple adverse childhood experiences (ACEs) show reduced brain volume in key emotional and cognitive regions well into mid- and late adulthood, and these changes don't fully explain the link between …

52 Promising
Design 8
Sample 13
Peer Review 13
Replication 6
Transparency 12

How We Identify With Others During Trauma: A Bridge Between Psychology and Biology

This paper argues that 'identification'—feeling a sense of sameness with another person—is a fundamental mental process rooted in both psychology and brain biology, especially important when we're under stress or trauma. The authors propose that …

30 Early
Design 4
Sample 2
Peer Review 10
Replication 5
Transparency 9

How Personality Traits Affect Emotion Control in Older Adults

This study of 210 older adults found that problematic personality traits are more strongly linked to difficulty *managing* emotions than to how often people *use* specific coping strategies. Different personality problems showed distinct patterns—for example, …

43 Early
Design 8
Sample 10
Peer Review 11
Replication 5
Transparency 9

A Lifetime of Learning May Protect Against Alzheimer's Disease

A study of nearly 2,000 older adults found that people with greater cognitive enrichment over their lifetime—like education, mentally stimulating activities, and learning—had a 38% lower risk of developing Alzheimer's dementia and delayed its onset …

53 Promising
Design 11
Sample 13
Peer Review 15
Replication 5
Transparency 9