How We Score
How we vet the research — transparency first
Preliminary
Can We Restore Aging Immune Systems to Make Cancer Drugs Work Better?
This is a thoughtful overview of promising but unproven strategies to restore immune function in older cancer patients, not a definitive study showing they work. The real test will come …
36
/100
This is a review/commentary article with no original data, making it unsuitable for drawing definitive conclusions. The cited trials are …
Preliminary
A protein that clears harmful RNA buildup could be key to aging
A newly discovered enzyme prevents aging-related RNA damage in animals, suggesting a promising target for longevity therapies—but this finding is too recent to confirm and needs independent replication before clinical …
46
/100
This is a very recent publication (Feb 2026) with zero citations—replication has not yet occurred. The abstract emphasizes mouse data …
Preliminary
How Caloric Restriction Reshapes Your Metabolism Over 2 Years
This well-designed study provides the first detailed snapshot of metabolic changes during long-term caloric restriction in humans, showing that carbohydrate and fat metabolism shift in time-dependent ways. However, as an …
39
/100
Major limitations: Preprint status with zero citations—no peer review yet. Descriptive/observational in nature; cannot prove causation or functional significance. Cannot …