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LongevityResearchHub

All Verified Promising Preliminary Disputed

Preliminary

Phytochemicals modulating HSF-1-associated pathways: A systematic review of longevity-extending mechanisms in Caenorhabditis elegans.

38 /100

Preliminary

Molecular signatures of the gut microbiota that affect longevity.

38 /100

Preliminary

CPT2 as a Convergent Node Linking Age-Associated Neuronal H3K27me3 Remodeling to Nicotinamide Mononucleotide (NMN)-Induced Expression Rescue in Metabolic Tissues.

38 /100

Preliminary

Prevention of Vascular Aging as a Novel Paradigm for GLP-1 Receptor Agonist-Mediated Cardioprotection.

38 /100

Preliminary

Sustained epigenetic rejuvenation of serially engrafting human iPSC-derived HSCs

34 /100

Preliminary

Sequelae and reversal of age-dependent alterations in mitochondrial dynamics via autophagy enhancement in reprogrammed human neurons

34 /100

Preliminary

Mitochondrial structural and functional defects in the Drosophila melanogaster model of PLA2G6 Associated Neurodegeneration (PLAN)

39 /100

Preliminary

Elevated BrainAGE precedes cognitive impairment and improves prediction of future cognitive decline

34 /100

Preliminary

OGT as a metabolic-epigenetic integrator in cancer: context-dependent mechanisms and therapeutic vulnerabilities.

38 /100

Preliminary

Harnessing Neutrophil Plasticity: From Mechanistic Insights to Oncology Therapeutics.

38 /100

Preliminary

Surface activation of Ti6Al4V via vacuum versus conventional ultraviolet photofunctionalization: physicochemical and biological insights.

38 /100

Preliminary

SOX10-mediated regulation of the MiR-106a/363 cluster drives RAF inhibitor resistance in BRAF-mutant melanoma.

46 /100

Preliminary

LKB1/ AMPK deficiency aggravates mitochondrial DNA leakage via mTOR-dependent mitophagy damage in liver injury sensitized by trichloroethylene.

38 /100

Preliminary

A derivative of cytisine N-isoflavone from Sophora alopecuroides L., suppresses non-small cell lung cancer by targeting mTOR.

38 /100

Preliminary

Decoding the PI3K/Akt/mTOR-JAK/STAT signaling axis in multiple sclerosis: mechanistic crosstalk and therapeutic opportunities.

38 /100

Preliminary

Manganese overload as a previously underappreciated trigger of cellular senescence: unraveling mechanisms and therapeutic rescue by the senolytic quercetin.

38 /100

Preliminary

The Spontaneous Evolution of Biology

34 /100

Preliminary

WAC loss alters food-associated behavior and physiological homeostasis with stage-associated cholinergic dysregulation in Caenorhabditis elegans

39 /100

Preliminary

Diabetic cardiomyopathy: Target immune cell from mechanism to treatment.

38 /100

Preliminary

Individualized HIFU in women over 60: ultrasound assessment of layer-specific facial soft-tissue thickness changes.

38 /100