Researchers found that SARS-CoV-2 infection disables a cellular growth regulator called mTORC1, which causes host cells to stop making most of their own proteins while still allowing viral proteins to be produced. This mechanism was …
Researchers discovered that telomerase doesn't just work on the finished ends of chromosomes—it also repairs breaks that happen *during* DNA replication at chromosome tips, and does so much more frequently than previously thought. This challenges …
This study reveals how a fungus (Neurospora crassa) uses two cellular signaling pathways to coordinate cell fusion—one pathway activates the machinery for building cellular structures, while the other aims that machinery at the right location. …
Researchers used advanced imaging and mass spectrometry to map how insulin receptors behave in muscle cells, discovering they travel via two different cellular pathways—one involving caveolin and one involving clathrin. This fundamental understanding of insulin …
Researchers found that a protein called TFAM, which manages mitochondria in regulatory T cells (immune cells that calm inflammation), is critical for preventing age-related systemic inflammation and physical decline. When mitochondrial function deteriorates in these …
This is a ornithological ecology study about where Black Woodpeckers excavate cavities in French forests—it has no relevance to human aging, lifespan, or longevity research. The analysis examined landscape and forest composition factors across three …
Researchers grew human pluripotent stem cells on circular patterns and watched them spontaneously organize into distinct midbrain and hindbrain regions—without being explicitly programmed to do so. This self-organizing system could help screen for birth defects …
Researchers discovered that LRRK2, a protein linked to Parkinson's disease, plays a critical role in strengthening connections between neurons by reorganizing the cellular skeleton in response to brain growth signals. This work identifies synaptic dysfunction—not …
Researchers discovered that aging cells shed large fragments containing damaged organelles through a process that keeps the cells alive but deposits cellular debris that activates cancer and wound-healing programs. This reveals a double-edged mechanism: senescent …