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LongevityResearchHub

All Verified Promising Preliminary Disputed

Preliminary

Partial reduction of the mitochondrial lipoyltransferase LipT2 promotes longevity and redox remodeling in Drosophila.

44 /100

Preliminary

Reactivation of a dormant developmental plasticity program drives synaptic rejuvenation and antidepressant-like responses

34 /100

Preliminary

Fitness effects of copper selection in a wild-derived population of Drosophila melanogaster

34 /100

Preliminary

Glycolytic compensation rather than NAD+/NADH balance sustains neuronal function during mitochondrial stress

34 /100

Preliminary

Disruption of the insulin/IGF-1 signaling pathway in Caenorhabditis elegans dramatically increases male longevity and enhances reproductive health late in life.

44 /100

Preliminary

Lipid metabolism and chromatin-associated sirtuin-dependent epigenetic reprogramming in cancer.

38 /100

Preliminary

Unraveling the epigenetic code in cancer cell-tumor microenvironment crosstalk.

38 /100

Preliminary

Decoding the multidimensional landscape of skin aging: molecular pathways and next-generation diagnostics & therapeutics.

38 /100

Preliminary

HIRA loss is frequent but not universal in human fumarate hydratase-deficient renal cell carcinoma and defines divergent oncogenic programs.

43 /100

Preliminary

The Grandmother Hypothesis: A Perspective from Cardiovascular Aging.

38 /100

Preliminary

miR-486-5p suppresses autophagy in hepatocellular carcinoma via activation of the AKT/mTOR signalling pathway.

38 /100

Preliminary

Role of epigenetic factors during blockade of the Renin-Angiotensin system across aging.

38 /100

Preliminary

How I Do It: Surgical Face and Neck Rejuvenation.

38 /100

Preliminary

Radiofrequency Microneedling Combined With Topical Extracellular Vesicle Preparation for Facial Rejuvenation: A Randomized Split-Face Controlled Study.

38 /100

Preliminary

Nicotinamide Mononucleotide (NMN) Prevents Age-Associated Transcriptional Drift in a Tissue-Dependent Manner: Mechanistic Leads From Ras-Related Protein Rab-11A-Mediated Trafficking and Carnitine Palmitoyltransferase 2-Linked Fatty Acid Oxidation.

38 /100

Preliminary

Development and Clinical Application of a Thermally Reconstructed Platelet-Rich Plasma Concentrate-Based Biofiller (ExoFiller).

38 /100

Preliminary

Puerarin extends lifespan and enhances the resistance to oxidative stress through AMPK/TFEB mediated autophagy in Caenorhabditis elegans.

44 /100

Preliminary

Systematic Errors in DC Offset Measurement and Mitigation at Neurostimulation Electrodes: Causes, Implications and Solutions

39 /100

Preliminary

Developmental programming of skeletal muscle aging by parental exercise: Intergenerational mechanisms and implications for lifelong muscle health.

38 /100

Preliminary

Exercise and p21 Signaling in Central Nervous System Aging and Senescence: A Context- and Dose-Dependent Relationship.

38 /100