Verified Pharmacological — Drugs and compounds that may slow or reverse aging. Rapamycin, metformin, NAD+ … Randomised Controlled Trial PubMed

Rapamycin Low-Dose Safety Profile in Healthy Elderly

Weekly low-dose rapamycin was well-tolerated in adults over 70, with improved immune function markers.

The Lancet Healthy Longevity Feb 12, 2026 n=150
81 Strong
Design 16
Sample 16
Peer Review 18
Replication 14
Transparency 17
How we score →
Promising Pharmacological — Drugs and compounds that may slow or reverse aging. Rapamycin, metformin, NAD+ … Randomised Controlled Trial PubMed

NAD+ Precursors Show Promise in Human Trials

NMN supplementation increased blood NAD+ levels by 40% in middle-aged adults, with improvements in insulin sensitivity.

Science Feb 12, 2026 n=80
74 Promising
Design 17
Sample 14
Peer Review 18
Replication 10
Transparency 15
How we score →
Verified Cellular — Research on cellular-level aging mechanisms Randomised Controlled Trial PubMed

Senolytics Extend Healthspan in Mice by 30%

A combination of dasatinib and quercetin cleared senescent cells in aged mice, resulting in improved physical function and extended healthy lifespan by approximately 30%.

Nature Medicine Feb 12, 2026 n=120
78 Strong
Design 18
Sample 15
Peer Review 17
Replication 12
Transparency 16
How we score →