Mitochondrial Transplantation Restores Muscle Function

Injection of healthy mitochondria into aged muscle tissue restored ATP production and contractile strength.

61 Promising
Design 14
Sample 12
Peer Review 17
Replication 5
Transparency 13

Time-Restricted Eating Reduces Inflammatory Markers

Limiting food intake to an 8-hour window reduced CRP and IL-6 levels by 25% in overweight adults.

77 Strong
Design 17
Sample 17
Peer Review 16
Replication 12
Transparency 15

Telomere Extension via AAV Gene Therapy in Primates

Single injection of telomerase gene therapy extended telomeres by 20% in macaques.

62 Promising
Design 15
Sample 8
Peer Review 19
Replication 6
Transparency 14

Rapamycin Low-Dose Safety Profile in Healthy Elderly

Weekly low-dose rapamycin was well-tolerated in adults over 70, with improved immune function markers.

81 Strong
Design 16
Sample 16
Peer Review 18
Replication 14
Transparency 17

NAD+ Precursors Show Promise in Human Trials

NMN supplementation increased blood NAD+ levels by 40% in middle-aged adults, with improvements in insulin sensitivity.

74 Promising
Design 17
Sample 14
Peer Review 18
Replication 10
Transparency 15

Senolytics Extend Healthspan in Mice by 30%

A combination of dasatinib and quercetin cleared senescent cells in aged mice, resulting in improved physical function and extended healthy lifespan by approximately 30%.

78 Strong
Design 18
Sample 15
Peer Review 17
Replication 12
Transparency 16